Does Humira cause hair loss?
It is unclear if Humira (adalimumab) causes hair loss and if so, in which populations. Hair loss was not a side effect reported in the clinical studies for Humira, a tumor necrosis factor (TNF) inhibitor. However, after the drug was approved, some people reported alopecia (hair loss) after taking Humira. As these post-approval reactions are voluntarily reported from a population of patients of unknown size, the data collected is limited and has not shown that the hair loss was a direct result of Humira use. In addition, some case reports in medical journals have linked Humira to hair loss.
On the other hand, there is some evidence, largely case reports in medical journals, that adalimumab may help treat alopecia in some people. Researchers postulate that the way someone’s genes interplay with the medication and a person’s level of tumor necrosis factor (TNF) may help explain why the drug may be linked to hair loss in some people yet hair growth in others. More research is needed to fully assess this link.
The most common side effects of Humira include:
- Upper respiratory/sinus infections
- Injection site reactions (pain, redness, swelling, itching, burning, rash)
- Headache
- Rash
- Nausea
References
- U.S Food and Drug Administration (FDA). Humira. December 2018. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/125057s410lbl.pdf [Accessed June 9, 2022]
- Abbvie. Humira: Important Safety Information. Available at: https://www.humira.com/#isi-anchor [Accessed June 9, 2022]
- Zschoche C, Bidier M, Hadaschik E. Alopecia areata during treatment with adalimumab: therapy with an alternative TNF-alpha inhibitor is possible. J Dtsch Dermatol Ges. 2013 May;11(5):450-3. https://doi.org/10.1111/ddg.12027
- Gorcey L, Spratt EAG, Leger MC. Alopecia Universalis Successfully Treated With Adalimumab. JAMA Dermatol. 2014;150(12):1341–1344. doi:10.1001/jamadermatol.2014.1544. https://jamanetwork.com/journals/jamadermatology/fullarticle/1913664
Read next
What happens when you stop taking Humira?
If you stop taking Humira. your medical condition may worsen. Withdrawal side effects are not likely to occur with Humira, but your signs or symptoms (based on your condition), like joint pain and inflammation, stomach pain or diarrhea, or structural joint damage may worsen or return. Do not stop taking Humira unless you and your doctor agree this is the best course of action. Continue reading
How much does Humira cost without insurance?
The average cash price of Humira (generic name: adalimumab) without insurance is around $7,300 for 1 carton (2 pens) of 40 mg/0.4 mL using an online coupon, but most people do not pay this much. Your actual cost will depend upon which Humira product you need, your coupon savings, if you have insurance, and any manufacturer's savings. Continue reading
Does Humira cause weight gain or weight loss?
The manufacturer of Humira does not list weight gain or weight loss as a possible direct side effect associated Humira. However, other conditions, symptoms, or medications may affect your weight while you are using this medication. Clinical studies have also shown weight gain with Humira. Continue reading
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Drug information
- Humira Information for Consumers
- Humira prescribing info & package insert (for Health Professionals)
- Side Effects of Humira (detailed)
Related support groups
- Humira (69 questions, 369 members)