How long does a Tysabri infusion take?

Yes, treatment with Tysabri can weaken your immune system. This may increase your risk of getting an unusual or serious infection. Tysabri increases the risk of progressive multifocal leukoencephalopathy (PML), a rare brain infection. If you have or have had PML, you cannot use Tysabri. Continue reading

You can take Tysabri for as long as you want providing you tolerate it well, have not developed any serious side effects, and Tysabri is still preventing relapses if you have multiple sclerosis (MS) or reducing symptoms, if you have Crohn’s disease. For people with MS, some response is noted at 12 weeks, but it may take up to 2 years for the full effects to be seen. People with Crohn’s disease should discontinue Tysabri if there is no benefit after 12 weeks Continue reading

Tysabri is not chemotherapy, it is a targeted treatment that works by blocking the migration of lymphocytes (a type of immune cell) from the lymph nodes, across the epithelium, and into inflamed tissue. It binds to a receptor that is present on all leukocytes apart from neutrophils and prevents them from binding to their counter receptors. It may also act in several other ways to prevent the further recruitment and inflammatory activity of activated immune cells. Tysabri belongs to the class of medicines known as integrin receptor antagonists. It may also be called a selective immunosuppressant or a monoclonal antibody. Continue reading