Secnidazole Dosage
Medically reviewed by drugclasses.com. Last updated on May 6, 2024.
Applies to the following strengths: 2 g
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Bacterial Vaginosis
2 g orally once
Use: For the treatment of bacterial vaginosis in female patients
Usual Adult Dose for Trichomoniasis
2 g orally once
Comments:
- Sexual partners of infected patients should be treated with the same dose at the same time to prevent reinfection as trichomoniasis is a sexually transmitted disease with potentially serious sequelae.
Use: For the treatment of trichomoniasis due to Trichomonas vaginalis
Usual Pediatric Dose for Bacterial Vaginosis
12 years or older: 2 g orally once
Use: For the treatment of bacterial vaginosis in female patients
Usual Pediatric Dose for Trichomoniasis
12 years or older: 2 g orally once
Comments:
- Sexual partners of infected patients should be treated with the same dose at the same time to prevent reinfection as trichomoniasis is a sexually transmitted disease with potentially serious sequelae.
Use: For the treatment of trichomoniasis due to T vaginalis
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
- Known hypersensitivity to the active component or other nitroimidazole derivatives
- Cockayne syndrome
Safety and efficacy have not been established in patients younger than 12 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Administer a single packet of granules; sprinkle the entire contents of the packet onto applesauce, yogurt, or pudding.
- Consume the entire mixture of food and granules within 30 minutes of preparation; do not chew or crunch the granules.
- May administer without regard to the timing of meals
- After consuming this drug, may drink a glass of water (to help with swallowing)
Reconstitution/preparation techniques:
- The entire contents of 1 packet should be sprinkled onto applesauce, yogurt, or pudding; the granules will not dissolve.
- The granules are not intended to be dissolved in any liquid.
General:
- A single packet of granules contains 2 g of this drug.
- To reduce the development of drug-resistant organisms and maintain effective therapy, this drug should be used only to treat or prevent infections proven or strongly suspected to be caused by susceptible bacteria.
- Culture and susceptibility information should be considered when selecting/modifying antibacterial therapy or, if no data are available, local epidemiology and susceptibility patterns may be considered when selecting empiric therapy.
Patient advice:
- Read the US FDA-approved patient labeling (Patient Information and Instructions for Use).
- Do not consume alcoholic beverages or products containing ethanol or propylene glycol during treatment and for at least 48 hours after completing therapy; nausea, vomiting, diarrhea, abdominal pain, dizziness, and headache may occur.
- Do not breastfeed during treatment or for 96 hours after dose administration.
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