Steglujan Dosage
Generic name: ERTUGLIFLOZIN PIDOLATE 5mg, SITAGLIPTIN PHOSPHATE 100mg
Dosage form: tablet, film coated
Drug class: Antidiabetic combinations
Medically reviewed by drugclasses.com. Last updated on Jun 28, 2024.
Prior to Initiation of STEGLUJAN
- Assess renal function prior to initiation of STEGLUJAN and as clinically indicated [see Warnings and Precautions (5.4)].
- Assess volume status. In patients with volume depletion, correct this condition before initiating STEGLUJAN [see Warnings and Precautions (5.5), Use in Specific Populations (8.5, 8.6)].
Recommended Dosage
- The recommended starting dose of STEGLUJAN is 5 mg ertugliflozin/100 mg sitagliptin once daily, taken in the morning, with or without food.
- For patients treated with ertugliflozin who are being switched to STEGLUJAN, the dose of ertugliflozin can be maintained.
- For additional glycemic control, the dose may be increased to 15 mg ertugliflozin/100 mg sitagliptin once daily in patients tolerating STEGLUJAN.
- Use is not recommended in patients with an eGFR less than 45 mL/min/1.73 m2.
- Use of STEGLUJAN is contraindicated in patients with severe renal impairment (eGFR less than 30 mL/min/1.73 m2), end-stage renal disease (ESRD) or on dialysis [see Contraindications (4)].
2.3 Temporary Interruption for Surgery
Withhold STEGLUJAN for at least 4 days, if possible, prior to major surgery or procedures associated with prolonged fasting. Resume STEGLUJAN when the patient is clinically stable and has resumed oral intake [see Warnings and Precautions (5.1) and Clinical Pharmacology (12.2)].
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