What are the ingredient drugs contained in Qternmet XR?
Qternmet XR contains dapagliflozin, saxagliptin and metformin hydrochloride in an extended-release tablet formulation. It was used in the treatment of adults with type-2 diabetes, but has now been discontinued.
Qternmet XR was available as extended-release tablets in the following strengths:
- dapagliflozin 2.5 mg / saxagliptin 2.5 mg / metformin hydrochlporide 1000 mg
- dapagliflozin 5 mg / saxagliptin 2.5 mg / metformin hydrochlporide 1000 mg
- dapagliflozin 5 mg / saxagliptin 5 mg / metformin hydrochlporide 1000 mg
- dapagliflozin 10 mg / saxagliptin 5 mg / metformin hydrochlporide 1000 mg
Qternmet XR was the first combination containing all three drugs. Dapagliflozin, saxagliptin and metformin hydrochloride are also contained in single ingredient products and combinations containing two of the drugs.
Dapagliflozin is a sodium-glucose cotransporter-2 (SGLT-2) inhibitor. Dapagliflozin is also contained in the following single ingredient and combination drug products:
- dapagliflozin (Farxiga)
- dapagliflozin and saxagliptin (Qtern)
- dapagliflozin and metformin hydrochloride (Xigduo XR)
Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. Saxagliptin is also contained in the following single ingredient and combination drug products:
- saxagliptin (Onglyza)
- dapagliflozin and saxagliptin (Qtern)
- saxagliptin and metformin hydrochloride (Kombiglyze XR)
Metformin hydrochloride is a biguanide. Metformin hydrochloride is also contained in the following single ingredient and combination drug products:
- metformin hydrochloride (Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet)
- dapagliflozin and metformin hydrochloride (Xigduo XR)
- saxagliptin and metformin hydrochloride (Kombiglyze XR)
Related questions
Read next
Why does metformin cause diarrhea?
According to the manufacturer, about 53% of people taking metformin immediate-release tablets experienced diarrhea in one clinical study. In another study, 10% of people taking metformin extended-release tablets reported diarrhea as a side effect. Continue reading
Does metformin cause weight loss?
Metformin, an oral type 2 diabetes medicine, may lead to a modest weight loss and does not usually lead to significant, if any, weight gain. In various clinical studies, when metformin was used alone, it led to a weight loss of 0.7 to 3.8 kg (1.5 to 8.4 lbs) in most patients, but other studies have shown weight loss up to 5.8 kg (12.8 lbs). Continue reading
Can you take metformin without food?
If you take metformin without food you may end up with an upset stomach, especially if you are just starting treatment. Nausea and vomiting is one of the most common side effects with metformin and can occur in over a quarter of patients. Continue reading
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