How much does Epclusa cost?
The cost of Epclusa (sofosbuvir and velpatasvir) tablets is roughly $US78,078 for a full 12-week course of treatment. Your cost might vary based on insurance or manufacturer-provided discounts. Epclusa is covered by most insurance plans.
For more information, see Epclusa Prices, Coupons and Patient Assistance Programs.
Epclusa was the first direct-acting oral antiviral agent approved to treat all six major forms of hepatitis C virus (HCV).
Epclusa is used to treat adult and pediatric patients 3 years of age and older with chronic HCV genotype 1, 2, 3, 4, 5, or 6 infection:
- without cirrhosis or with compensated cirrhosis
- with decompensated cirrhosis for use in combination with ribavirin
Epclusa tablets are used to treat patients weighing at least 17kg. Epclusa oral pellets have also been approved to treat children unable to swallow tablets.
Epclusa is taken once daily for 12 weeks.
Epclusa is a fixed-dose combination containing sofosbuvir and velpatasvir. An authorized generic version of sofosbuvir and velpatasvir tablets was launched in 2019. It is available from Asegua Therapeutics, a subsidiary of the company that also makes Epclusa. At the time of the launch of the generic, the list price for it was $US24,000.
References
- Epclusa. Savings on Epclusa. Available from: https://www.epclusa.com/saving-on-epclusa. [Accessed February 21, 2021].
- Food and Drug Administration (FDA). Epclusa. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/208341s017lbl.pdf. [Accessed June 15, 2021].
- Gilead. Gilead Subsidiary to Launch Authorized Generics of Epclusa® (Sofosbuvir/Velpatasvir) and Harvoni® (Ledipasvir/Sofosbuvir) for the Treatment of Chronic Hepatitis C. September 24, 2018. Available from: https://www.gilead.com/news-and-press/press-room/press-releases/2018/9/gilead-subsidiary-to-launch-authorized-generics-of-epclusa-sofosbuvirvelpatasvir-and-harvoni-ledipasvirsofosbuvir-for-the-treatment-of-chronic. [Accessed February 15, 2021].
Read next
What is the difference between hepatitis B and C?
Some of the main differences between hepatitis B and C are:
- Hepatitis B virus can be prevented with a vaccine, but not hepatitis C.
- Hepatitis B and C are different viruses, but you can have both hepatitis B and hepatitis C at the same time.
- Over 90% of people infected with hepatitis C who have not received treatment can be cured with 8 to 12 weeks of oral medications, but treatment for hepatitis B, if needed, may be long-term or lifelong.
- There is no cure for hepatitis B, but once you recover from acute hepatitis B, you develop antibodies that protect you from the virus for life.
What are the new drugs for the treatment of hepatitis C?
The newest drugs for the treatment of hepatitis C include Mavyret (glecaprevir and pibrentasvir), Vosevi (sofosbuvir, velpatasvir, and voxilaprevir), and Epclusa (sofosbuvir and velpatasvir). All are FDA-approved for the treatment of chronic hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with compensated cirrhosis (Child-Pugh A), as well as other uses. Continue reading
Does Epclusa work if you miss doses?
There is a chance that Epclusa may not work as well if you miss doses. Epclusa works by interfering with a protein and an enzyme needed by the hepatitis C virus to replicate and if you forget a dose, your blood levels of Epclusa can fall below the level needed to inhibit this protein or enzyme. Continue reading
Related medical questions
- What is the best time of day to take Epclusa?
- Does Epclusa cure Hep C, what is the success rate?
- How long is an Epclusa treatment?
- How long does Epclusa stay in your system?
- Can you drink alcohol while taking Epclusa?
- Epclusa vs Harvoni – Which is better?
- How does Epclusa work in the body?
- What is the difference between Vosevi and Epclusa?
Drug information
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