How long does it take for Jaypirca to work?
Jaypirca (pirtobrutinib) starts working quickly after you take it. However, it can take up to a few months for some people to see the full effects of the medication. In studies, patients taking Jaypirca saw their cancer shrink in size and stop spreading as early as 7 weeks for chronic lymphocytic leukemia and 3.5 weeks for mantle cell lymphoma.
Chronic lymphocytic leukemia
- In a clinical trial of adult patients who had received at least two treatments and taking Jaypirca for chronic lymphocytic leukemia, some patients saw their cancer shrink and stop spreading around 7 weeks after they started treatment.
- The median time it took for patients taking Jaypirca to see their cancer shrink in size and stop spreading was 3.7 months.
- The range of time it took patients to see their cancer shrink in size and stop spreading was 1.7 months to 27.9 months.
Mantle cell lymphoma
- In a clinical trial of adult patients who had received at least two treatments and taking Jaypirca for mantle cell lymphoma, some patients saw their cancer stop spreading and reduce in size as early as 3.5 weeks after they started treatment.
- The median time it took for patients taking Jaypirca to see their cancer shrink and stop spreading was 1.8 months.
- The range of time it took for patients to see their cancer shrink in size and stop spreading was 3.5 weeks to 4.2 months.
Related questions
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How does Jaypira work?
Jaypirca is a BTK inhibitor. BTK is a protein that signals activation of cancerous B-cells to multiply. By blocking BTK, Jaypirca stops cancer cells from multiplying and spreading in the body.
This is not all the information you need to know about Jaypirca (pirtobrutinib) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.
References
Jaypirca [package insert]. Updated June 2024. Eli Lilly and Company. Accessed August 6, 2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bd551845-0878-49a4-860f-839b83f6b801
jaypirca.lilly.com. Jaypirca for CLL. n.d. Accessed August 6, 2024 at https://jaypirca.lilly.com/jaypirca-for-cll
jaypirca.lilly.com. Jaypirca for MCL. n.d. Accessed August 6, 2024 at https://jaypirca.lilly.com/jaypirca-for-mcl
Read next
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Hair loss (alopecia) has not been noted as a side effect of ibrutinib (Imbuvica) in the product label. Textural hair changes (softening, straightening or curliness) and nail changes (brittle fingernails and toenails) were noted in a study evaluating ibrutinib use over the long term for treatment of chronic lymphocytic leukemia (CLL). Continue reading
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You could expect Velcade to stay in your system ranging from 9 days (220 hours) to 44 days (1061 hours) depending on which dose you receive. Continue reading
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Drug information
- Jaypirca Information for Consumers
- Jaypirca prescribing info & package insert (for Health Professionals)
- Side Effects of Jaypirca (detailed)
Related support groups
- Jaypirca (1 questions, 3 members)
- Mantle Cell Lymphoma (10 questions, 9 members)
- Chronic Lymphocytic Leukemia (CLL) (26 questions, 57 members)