If you are taking lamotrigine how long does it take to get out of your system?
Medically reviewed by drugclasses.com. Last updated on Nov 2, 2023.
Lamotrigine will be out of your system after your last dose in about 338.8 hours (approximately 14 days).
After multiple dosing (in volunteers who took no other medicines) of lamotrigine the elimination half-life is noted to be between 11.6 to 61.6 hours.
It takes approximately 5.5 x elimination half-life for a medicine to be cleared from your body which for lamotrigine would take 5.5 x half life (5.5 x 61.6 hours (max)) 338.8 hours.
However other factors to consider include:
1. How much and how often you have taken the drug.
2. Your metabolic rate – a slower metabolism will increase the time a drug remains in your system.
3. Your age and health – older age and poor health will generally increase the time the drug stays in your system.
4. Body mass – generally the bigger you are the longer a drug will remain in your system.
Read next
Is it better to take lamotrigine at night?
You should take lamotrigine at night if it makes you sleepy and if you are prescribed it once a day. But if it doesn’t make you sleepy or if it tends to keep you awake, then take it first thing in the morning. If you are prescribed lamotrigine twice a day, then space out the dosages as much as you can, which means taking one dose first thing in the morning and one dose at night. Continue reading
What should I do if I develop a rash while taking lamotrigine?
Contact your healthcare provider or other emergency medical services right away if you develop a skin rash, blistering or peeling of your skin, hives, painful sores in your mouth or around your eyes or other signs of a drug allergy (such as a fever or swelling of your lymph nodes) while taking lamotrigine. This could signal you are having a serious side effect to lamotrigine which may result in hospitalization or cause death. Continue reading
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Venlafaxine withdrawal symptoms typically last up to 3 to 4 weeks, but may persist even longer. You should avoid abruptly stopping venlafaxine treatment unless otherwise directed by your healthcare provider. Gradually reducing the dose over 4 weeks can help to prevent severe withdrawal symptoms in most people. Continue reading
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Drug information
- Lamotrigine Information for Consumers
- Lamotrigine prescribing info & package insert (for Health Professionals)
- Side Effects of Lamotrigine (detailed)
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