How long does it take gabapentin to work?
It can take several weeks for gabapentin to reach its full effect, but this depends on the condition being treated. Gabapentin is approved to treat:
- Nerve pain
- Some types of seizures
- Restless legs syndrome (RLS)
It also depends on your individual response to the drug. The time gabapentin takes to work is not the same for everyone.
The effective dose of gabapentin is also very different for each person, and the condition they are treating. It may vary from 300 mg per day to up to 3,600 mg per day.
Another reason gabapentin takes time to work is that the dose is usually started low and gradually increased over time to reach an effective dose. For example, when used to relieve nerve pain, the initial dose may be started at 300 mg and increased by 300 mg daily over several days, gradually reaching up to 600 mg three times per day. Studies for nerve pain treatment show that pain relief may begin within 1 week, with the maximum effect reached after about 4 weeks.
Gabapentin is in a class of medications called anticonvulsants. It is not completely known how this drug works. When used to treat a type of seizure disorder, called a partial onset seizure, gabapentin decreases the abnormal activity in the brain that causes the seizures. When used to treat nerve pain, or neuralgia, following a herpes zoster (shingles) infection, gabapentin may reduce the response to painful stimuli. It is unknown how gabapentin relieves symptoms of restless legs syndrome.
Even though it may take up to 4 weeks to get the full effects of gabapentin, it is important not to stop taking it suddenly. That could cause withdrawal symptoms such as:
- Anxiety
- Insomnia
- Nausea
- Pain
If you are taking gabapentin to control seizures, stopping suddenly may increase your risk of a seizure.
Talk to your doctor if gabapentin is not working or causing side effects.
Related questions
References
- National Headache Foundation. Neurontin. Undated. Available at: https://headaches.org/2007/10/25/neurontin/. [Accessed March 5, 2021].
- U.S. National Library of Medicine. Gabapentin. May 15, 2020. Available at: https://medlineplus.gov/druginfo/meds/a694007.html. [Accessed March 5, 2021].
- Food and Drug Administration (FDA). Neurontin (gabapentin). October 2017. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020235s064_020882s047_021129s046lbl.pdf. [Accessed March 5, 2021].
- Pfizer. Gabapentin. December 2020. Available at: labeling.pfizer.com/ShowLabeling.aspx?id=630. [Accessed March 5, 2021].
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How long does gabapentin withdrawal last?
Case reports have shown that gabapentin withdrawal often lasts for 5 to 10 days, but some people have taken as long as 18 weeks to completely taper off gabapentin while managing withdrawal symptoms. The symptoms and how long they last depend on how much of the drug you are taking and for how long you’ve been taking it. Continue reading
Does gabapentin cause weight gain?
Gabapentin may cause weight gain, but it is an uncommon side effect. Studies have shown that a small number of people taking gabapentin weight gain. People who do gain weight may gain about 5 pounds after 6 weeks of use. Continue reading
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Drug information
- Gabapentin Information for Consumers
- Gabapentin prescribing info & package insert (for Health Professionals)
- Side Effects of Gabapentin (detailed)
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