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Opill OTC vs other birth control pills: What's the difference?

Medically reviewed by Carmen Pope, BPharm. Last updated on Sep 22, 2023.

Official answer

by drugclasses.com

Opill is a progestin-only pill, which makes it different from other birth control pills that contain both estrogen and a progestin (such as Yaz, Junel FE, Lutera, or Sprintec) although you can get progestin-only pills (such as Cerazette, errin, and Heather) on prescription. Progestin-only pills are often called mini-pills, so Opill is a type of mini-pill.

Is Opill as effective as other birth control?

Progestin-only pills, including Opill, may have a slightly lower effectiveness compared to combination estrogen/progestin pills. To enhance their efficacy, it is recommended to take them consistently at the same time each day or within a 3-hour window of the same time daily. Progestin-only pills are often chosen for birth control by individuals who cannot take estrogen, including those who are breastfeeding.

How does Opill work?

Opill prevents conception in several different ways:

  • Thickening cervical mucus to inhibit sperm penetration
  • Lowering the midcycle LH and FSH peaks
  • Slowing the movement of the egg through the fallopian tubes
  • Altering the lining of the endometrium
  • Suppressing ovulation in approximately half of the menstrual cycles of females who use it.
References
  • Opill Tablets https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/017031s035s036lbl.pdf

Read next

How much does Opill cost?

Opill costs $19.99 for a 1-month (28 pill) pack, $49.99 for a 3-month (84 pill) pack and $89.99 for a 6-month (168 pill) pack. The 3- and 6-month packs are available online, and the 1- and 3-month packs are available on shelves at pharmacies and retail shops. Continue reading

How do I use Opill birth control?

Take 1 tablet at the same time every day. It is important to take your pill at the same time of day (and no later than 3 hours from the time you took your tablet the day before). Use a condom (or another barrier method) every time you have sex during the first 2 days (48 hours) because it takes 2 days for Opill to start working. Opill is NOT for use as an emergency contraceptive and will not prevent pregnancy after unprotected sex. Continue reading

How effective is Opill OTC birth control?

Opill is 93% effective at preventing pregnancy with typical use and 98% effective when used perfectly. As with any birth control method, Opill does not prevent pregnancy all of the time. Opill is NOT for use as an emergency contraceptive and will not prevent pregnancy after unprotected sex. Continue reading

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