What is tianeptine?

Tianeptine is a non-FDA-approved substance sold as a dietary supplement in gas stations and stores under names like Neptune’s Fix. It's sometimes referred to as "gas station heroin." Though not FDA-approved, it's technically legal in some U.S. states, but banned or restricted in others due to its opioid-like effects.

Abroad, countries like France reclassified it as a narcotic, while others, like Spain, have no restrictions. It's not approved in Australia, Canada, New Zealand, or the UK.

Tianeptine influences brain chemicals like serotonin, impacting mood and, at higher doses, acts like an opioid, leading to euphoria. It carries a high risk of addiction, with reports suggesting dependence can develop in as little as a few weeks.

Side effects range from mild, like headaches and constipation, to severe, including cardiovascular issues, liver and kidney damage, and even death. Withdrawal symptoms, akin to opioids, can be intense, requiring hospitalization. Overdosing on tianeptine, particularly in combination with other substances, can be fatal, necessitating emergency intervention like naloxone.

In 2023, 391 cases of tianeptine poisoning were reported in the U.S., underscoring its potential dangers.

For more information about tianeptine, click here.