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Is Xanax a narcotic (opioid) drug / controlled substance?

Medically reviewed by Sally Chao, MD. Last updated on June 25, 2024.

Official answer

by drugclasses.com

No, Xanax is not a narcotic. Xanax is a prescription medication in a class of drugs called benzodiazepines (benzos). While not a narcotic (opioid) itself, it’s possible it may be prescribed along with opioids, but this can be harmful.

Xanax is typically prescribed to relieve anxiety disorders, panic attacks or depression. Xanax works by calming the central nervous system and lowering overexcitement in the brain.

Xanax is a controlled substance. The active ingredient alprazolam is a Schedule IV controlled substance, which is less likely to be abused than a Schedule III drug, but it still has the potential for abuse.

The drug can become addictive, and it’s especially dangerous when prescribed with opioids. Opioids are typically prescribed to relieve pain. A 2016 study in Pain Medicine found that overdose death rates among patients taking opioids and benzos together were 10 times higher than among those only taking opioids.

Because of the dangers of mixing these drugs, in 2020 the U.S. Food and Drug Administration began to require "black box" warnings on the labels of benzodiazepines and opioids that warn of the dangers of using these drugs together. The Centers for Disease Control and Prevention recommends that doctors avoid prescribing Xanax and other benzodiazepines with opioid pain medication.

References
  1. Ait-Daoud N, Hamby AS, Sharma S, Blevins D. A Review of Alprazolam Use, Misuse, and Withdrawal. J Addict Med. 2018;12(1):4-10. doi:10.1097/ADM.0000000000000350. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846112/
  2. Drug Enforcement Administration (DEA). Controlled Substance Schedules. Available at: https://www.deadiversion.usdoj.gov/schedules/. [Accessed June 3, 2021].
  3. National Institute on Drug Abuse (NIDA). Benzodiazepines and Opioids. February 3, 2021. Available at: https://www.drugabuse.gov/drug-topics/opioids/benzodiazepines-opioids. [Accessed June 1, 2021].
  4. Dasgupta N, Funk MJ, Proescholdbell S, et al. Cohort Study of the Impact of High-Dose Opioid Analgesics on Overdose Mortality. Pain Med. 2016;17(1):85-98. https://doi.org/10.1111/pme.12907
  5. U.S. Food and Drug Administration (FDA). FDA requiring Boxed Warning updated to improve safe use of benzodiazepine drug class. September 23, 2020. Available at: https://www.fda.gov/drugs/drug-safety-and-availability/fda-requiring-boxed-warning-updated-improve-safe-use-benzodiazepine-drug-class. [Accessed June 1, 2021].
  6. Centers for Disease Control and Prevention (CDC). CDC Guideline for Prescribing Opioids for Chronic Pain. Available at: https://www.cdc.gov/overdose-prevention/hcp/clinical-guidance/index.html [Accessed June 2, 2021].

Read next

How long does Xanax last for / stay in your system?

One dose of Xanax can last anywhere from 31 hours to 134.5 hours (5.6 days) in the body, depending on factors related to the individual who took it. However, the calming, relaxing, and sedative effects of Xanax usually wear off within about eight to twelve hours. Continue reading

Does Xanax help you sleep?

Xanax (alprazolam) will cause sedation, drowsiness and somnolence as a side effect but is not typically prescribed to help with insomnia (trouble sleeping) on a regular basis. Sleepiness after taking Xanax usually occurs within 15 to 45 minutes. Continue reading

How does Xanax make you feel?

When taken as prescribed, Xanax (alprazolam) can help people with anxiety disorders or panic attacks by promoting a feeling of calm. It can also make you feel drowsy and lightheaded and may make you less mentally alert, so operating machinery and motor vehicles is not recommended while taking Xanax until you know how it makes you feel. Continue reading

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