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How often can you take Imitrex (sumatriptan)?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on June 20, 2024.

Official answer

by drugclasses.com

How often you can take Imitrex (sumatriptan) depends on which form you are taking. Imitrex comes as a tablet, nasal spray, and injection. Each form of Imitrex has its own specific dosing recommendations. Do not take more Imitrex than what’s prescribed to you, since taking too much can lead to serious side effects.

What is Imitrex (sumatriptan) used for?

Imitrex (sumatriptan) is FDA approved to treat migraines and cluster headaches in adults. It is also used off-label to treat migraines in children and cyclic vomiting syndrome.

How far apart should you take Imitrex (sumatriptan)?

  • Imitrex tablets: If your migraine did not get better within 2 hours after taking a dose, you may take a second dose at least 2 hours after the first dose. The maximum dose is 200 mg in a 24-hour period.
  • Imitrex nasal spray: If your migraine did not get better within 2 hours after taking a dose, you may take a second dose at least 2 hours after the first dose. The maximum dose is 40 mg in a 24-hour period.
  • Imitrex Statdose injection: If your headache or migraine has not fully responded to your first injection, you may use another injection at least 1 hour after the first. The maximum dose is 12 mg in a 24-hour period.

Related questions

Can I take Imitrex every day?

Imitrex is not meant to be taken every day. It should only be taken at the first sign of headache symptoms, and it should not be taken to prevent headaches or migraines. Taking Imitrex too often can lead to side effects, such as an increase in blood pressure, injection site reactions, nasal discomfort, and rebound headaches.

How many times can you use Imitrex in a month?

It isn’t known how safe it is to use Imitrex to treat more than 4 headaches per month on average. If you’re having more than 4 headaches or migraines per month, ask your doctor about the best treatment options.

Using migraine medications for 10 or more days per month can cause medication-overuse headaches (sometimes called rebound headaches). This means you could experience daily headaches or more frequent migraine attacks. Medications that may contribute to medication-overuse headaches include:

  • Triptans, like Imitrex
  • Ergotamine
  • Opioids
  • NSAIDs

Talk to your doctor about alternative treatments to prevent medication-overuse headaches. They can also recommend preventative options.

References

Brar, Y., et. al. (2023). Sumatriptan. In: StatPearls [Internet]. Accessed 06/20/2024 at https://www.ncbi.nlm.nih.gov/books/NBK470206/

Imitrex injection [package insert]. (Revised 2023). GlaxoSmithKline LLC. Accessed 06/19/2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fee7d073-0b99-48f2-7985-0d8cf970894b

Imitrex nasal spray [package insert]. (Revised 2022). GlaxoSmithKline LLC. Accessed 06/19/2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=cc11b09d-e6cc-4cf8-1495-5ac64d5aae5f

Imitrex tablet [package insert]. (Revised 2024). GlaxoSmithKline LLC. Accessed 06/19/2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=584abe73-8290-4484-ff8e-5890831c095e

Fischer, M. A., et. al. (2023). Medication-Overuse Headache. In: StatPearls [Internet]. Accessed 06/19/2024 at https://www.ncbi.nlm.nih.gov/books/NBK538150/

Read next

How long does Imitrex (sumatriptan) take to work?

Imitex (sumatriptan) can start to work within 30 minutes of taking a dose. However, it may take a few hours for you to notice the full effects. Continue reading

Can Imitrex (sumatriptan) cause rebound headaches?

Yes, Imitrex (sumatriptan) can cause rebound headaches (also known as medication-overuse headaches). Rebound headaches are more likely to occur if you take Imitrex alone or a combination of Imitrex and other headache medications (e.g., opioids, analgesics) for 10 or more days per month. Continue reading

Why does throwing up relieve migraines?

For many, vomiting can help relieve migraine symptoms, even stopping the headache altogether. Research suggests that vomiting stops migraines by alleviating gastric stasis (or gastroparesis), the delayed gastric emptying that causes stomach upset to occur over the course of a migraine. Continue reading

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