What type of drug is Pifeltro (doravirine)?
Pifeltro (doravirine) is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It is used for the treatment of HIV-1 infection.
Non-nucleoside reverse transcriptase inhibitors are antiviral agents that bind non-competitively to HIV-1 reverse transcriptase and prevent viral RNA conversion to DNA. These drugs work by preventing HIV from multiplying in the body. NNRTIs are used in combination with other antiretroviral medicines.
Pifeltro is indicated for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 35 kg:
- with no prior antiretroviral treatment history, OR
- to replace the current antiretroviral regimen in those who are virologically suppressed (HIV-1 RNA less than 50 copies per mL) on a stable antiretroviral regimen with no history of treatment failure and no known substitutions associated with resistance to doravirine.
Read next
Which medicines should not be taken with Biktarvy?
- Biktarvy is a complete regimen and use with other antiretroviral medications for the treatment of HIV-1 infection is not recommended.
- Biktarvy is associated with many drug interactions as it contains three different medicines, increasing your risk for interactions. Have your health care provider check for possible interactions with other prescription medicines, OTCs or herbal you take.
- You should not take Biktarvy with dofetilide (Tikosyn), a drug used for heart rhythm disorders or rifampin (Rifadin), a medicine for tuberculosis (TB). These drugs are contraindicated with the use of Biktarvy.
Who are the actors in the Dovato commercial?
Three real-life patients feature in the Dovato commercial “Detect This” released on May 23, 2022. They are Jovon [surname withheld], Ann Edwards, and Armando [surname withheld]. Continue reading
What is the recreational use of ART, including Truvada?
Recreational use of ART (Antiretroviral Therapy), including drugs like Truvada, is the non-prescribed consumption of these medications for their intoxicating effects. This dangerous practice has become a growing concern, particularly in regions with high HIV prevalence, such as South Africa. One survey of 200 adolescents reported that 3% used non-prescribed ART recreationally themselves and 14% knew someone who used it. Continue reading
Related medical questions
- What drugs are contained in the HIV treatment Delstrigo?
- How do you increase your CD4 count?
- What is an undetectable HIV viral load?
- Can Descovy be used for pre-exposure prophylaxis (PrEP) in HIV?
- Modafinil (Provigil) vs Adderall: What's the difference?
- Truvada vs Descovy: How do they compare for HIV and PrEP?
- What if I miss a dose of Biktarvy?
- Who are the actors in the Biktarvy commercials?
- How fast or how long does it take Biktarvy to work?
- Does Dovato cause weight gain?
- Is Biktarvy covered by insurance?
- Can I drink alcohol while taking Biktarvy?
- What do I need to know about Drug Interactions?
- How effective is Dovato for HIV?
- What is Biktarvy used for?
- Does Biktarvy cause hair loss?
- Apretude vs Cabenuva, what is the difference?
- What is the generic name for Biktarvy?
- What are 9 key Dovato side effects to watch out for?
- Can you crush Biktarvy tablets?
- What is the difference between Biktarvy and Descovy?
- Who are the actors in the Descovy commercial?
- What is the difference between Vemlidy and Viread?
- Does Biktarvy increase cholesterol?
- How does Truvada work to prevent HIV?
- Can Leronlimab (PRO 140) be used to treat COVID-19 (coronavirus)?
- Does Biktarvy cause acne?
- How long does Genvoya stay in your system?
- HIV Antiviral Drugs - What are the common side effects?
- What is Genvoya used to treat?
Drug information
Related support groups
- Doravirine (2 questions, 3 members)
- Pifeltro (2 questions, 3 members)
- HIV Infection (89 questions, 246 members)